Cell Viability

Lysosome Function, Cathepsin Activity, and Cell Viability Techniques

At ICT, we are on a mission to help cure disease and we do that by providing better assays to study lysosomal functionality, cell viability, and cathepsins. Watch this webinar to understand the role of lysosomes and cathepsins, and how they impact cell viability, apoptosis, autophagy, mitosis, and mitochondrial function.

What will you learn?

• How lysosome function is used as a reliable indicator of cell health and toxicity
• The activity of cathepsins inside lysosomes, in the cytosol, and in the extracellular matrix
• How cathepsins are tightly regulated to prevent uncontrolled proteolytic activity which can lead to diseases like cancer
• How lysosomes and cathepsins play a role in diseases such as Alzheimer’s, Parkinson’s, cancer, and malaria
• Impact of calcium to regulate pH in the lysosome
• Apoptosis, Autophagy, Mitosis, and Mitochondrial health
• Techniques to easily measure cathepsin activity and lysosome function in cultured cells, including neurons, with examples using microfluidic devices, and transgenic models using GFP