Cardiovascular Biomarkers

ELISA Kits for clinical research

Cardiovascular diseases are the most common cause of death worldwide and in Germany. However, if diagnosed in time, these diseases can usually be treated well. With our partners' high-quality ELISA kits for biomarker detection, we support your preclinical and clinical research on cardiovascular diseases.

 

FGF23: Novel Risk Marker of Heart Failure

FGF23 (fibroblast growth factor 23), a known marker of phosphate metabolism, has acquired independent importance in the cardiovascular system (Hu et al. 2013). Recent studies indicate that FGF23 is also expressed in the heart (Itoh et al., 2016). Elevated FGF23 levels are associated with cardiovascular mortality, higher risk of myocardial infarction, stroke, and heart failure. In addition, there is growing evidence that FGF23 levels may predict response to therapies to reduce the risk of heart failure (Brandenburg et al., 2014; Almahmoud et al., 2018). Further clinical studies are needed, but FGF23 is one of the few promising biomarkers that have the potential to determine the effect of FGF23-specific therapeutic interventions on clinically relevant endpoints (Vervloet et al., 2019).

Premium ELISA Kits for FGF23 detection:

BI-BI-20700	Biomedica FGF23 (intact) human ELISA
BI-BI-20702	Biomedica FGF23 (C-terminal) multi-matrix ELISA

 

big ET for the diagnosis of Heart Failure with preserved Ejection Fraction (HFpEF) 

Renal dysfunction may limit the clinical application of NT-proBNP in the diagnosis of heart failure. Big ENDOTHELIN (big ET) is an excellent biomarker candidate for the diagnosis of HFpEF in CKD, independent of GFR (Gergei et al., 2018). NT-proBNP is strongly associated with GFR and shows an exponential negative correlation with GFR decline, whereas Big ET-1 is much less affected. A single cut-off point is sufficient in the diagnosis of HFpEF in CKD.

BI-BI-20082H

Biomedica Big Endothelin ELISA

 

Other cardiovascular biomarker ELISA test kits for clinical and preclinical use:

BI-SK-1204	Biomedica NT-proBNP ELISA
BI-BI-20892	Biomedica NT-proANP ELISA
BI-BI-20812	Biomedica NT-proCNP ELISA
BI-BI-20403	Biomedica OPG ELISA
BI-BI-ANG2	Biomedica Angiopoietin-2 ELISA
BVD-RA05880R	BioVendor Angiotensin II Human/Rat ELISA
BVD-RCD032R	NEW: BioVendor Plasma Renin Activity ELISA
BVD-RAG006R	NEW: BioVendor ACE2 Human ELISA

 

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