UCS Diagnostics

Cytomatrix for preservation of cytological samples from fine needle aspirates (FNA)

UCS Diagnostic Srl has developed CytoMatrix at the Bio-Medico Campus of the University of Rome: A synthetic matrix that morphologically preserves biological material (cells, tumor biopsies) from fine needle aspirates (FNA) in their three-dimensional structure. This results in enormous benefits for routine diagnostics and offers new options for research.

Application
CytoMatrix (Art. Nr. CM140) is a porous support for trapping minimal amounts of cells , e.g. the material from a needle aspiration, and preserves structure (by formalin fixation and paraffin embedding), thus generating optimal conditions for various routine diagnostic tests: Hematoxylin-Eosin (H&E), Immunohistochemistry (IHC), Molecular Pathology (FISH).
CytoMatrix can easily allow the phenotypic characterization of small amounts of cancer cells and allows to faithfully preserve the features of the original tumour. This makes it an essential and in some cases indispensable and irreplaceable tool for a complete and accurate diagnosis.

Reference
Brushini S et al. CytoMatrix for a reliable and simple characterization of lung cancer stem cells from malignant pleural effusions. J Cell Physiol. 235(3): 1877–1887 (2020) / doi: 10.1002/jcp.29121


Dog: B Cell Lymphoma, CD20	Thyroid: ADENOMA	Ovarian Ca ascites (EGFR E746-A750 del.)	Breast needle aspiration EE	FNA Thyroid Perls Stain (40X)

Pulmonary needle aspiration ADC	Pleural effusion	Gastric GIST Antrum DOG1 (100X)	Pleural effusion from breast cancer	Urovysion on Urine

Cranial theca bone detail	Bone marrow aspirate: CD138, (plasma cells) 20X	ck7 in ascites of ovarian k	Lung ADK, PD-L1 (40X)	Pulmonary needle aspiration ADC